2021, Volume 17
Pro-inflammatory effect induced by regular wrestling training in women
1Józef Piłsudski University of Physical Education in Warsaw, Department of Human Biology, Warszawa, Poland
Author for correspondence: Teresa Walczyk; Józef Piłsudski University of Physical Education in Warsaw, Department of Human Biology, Warszawa, Poland; email: firstname.lastname@example.org
Background and Study Aim: Athletes are subjected to intense training to increase their performance and bring them closer to winning the competition. High intensity and time of physical exertion, combined with insufficient time for rest, may contribute to local and systemic inflammations. Thus, the purpose of this study was knowledge about the relationship between 17-week variable intensity and time of training and the concentrations of inflammatory markers.
Material and Methods: The study involved 12 women training wrestling (S) and 14 women not practising sports (NT). Blood was collected five times during a 17-week training with variable time and intensity. The counts of white blood cells and the concentration of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) and creatine kinase activity (CK) were carried out.
Results: A significant relationship between the number of monocytes and the date of the study (p<0.001). A significantly higher concentrations of IL-1β and IL-6 were found in the S group compared to the NT group at all study dates (p<0.001).
Conclusions: In contrary to expectations, apart from the number of monocytes, no correlation was found between the volume and intensity of exercise and the examined markers of inflammation. At the same time, constantly elevated basal levels of IL-1 β and IL-6 suggest a pro-inflammatory effect of exercise. It is recommended to observe the concentration of these cytokines and modify the training plan, extend the time spent on rest to allow to regain their immune balance.
Key words: interleukin-6, interleukin-1 beta, inflammation, C-reactive protein, blood cells, tumor necrosis factor alpha